[Local recurrence in soft tissue sarcoma: prognostic factors].

نویسندگان

  • Luiz Eduardo Moreira Teixeira
  • Ivana Duval Araújo
  • Marco Antônio Percope de Andrade
  • Rogério Andrade Gomes
  • Paulo Guilherme de Oliveira Salles
  • Daniel Ferreira Ghedini
چکیده

OBJECTIVE To determinate the prognostic factors associated with the local relapse in patients treated for soft tissue sarcoma in extremities. METHODS Retrospectively, 30 patients were evaluated after being treated with surgical resection of soft tissue sarcoma located in extremities, with a outcome of 36,5 +/- 12,2 months. The prognostic factors evaluated were: age, sex, location, depth, location in the anatomic compartments, size, tumor previous manipulation, surgical margins, grade of histological malignance, presence of histological necrosis or histological vascular invasion. These factors were correlated with the local relapse of the tumor with a univariated and multivariated analysis with significance when p = 0,05. RESULTS Local relapse presented significant correlation in univariated and multivariated analysis with extra-compartimental location (p = 0,001) and with high grade histological malignance (p = 0,001). There was no significant association with age (p = 1,000), sex (p = 1,000), body location (p = 0,544), depth (p = 0,288), size (p = 0,694), surgical margins (p = 0,384), previous manipulation (p = 0,461), necrosis (p = 0,461) or with the presence of vascular invasion (p = 1,000). CONCLUSION Local relapse presents correlation with extra-compartimental location and with high grade malignancy tumors.

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عنوان ژورنال:
  • Revista do Colegio Brasileiro de Cirurgioes

دوره 36 5  شماره 

صفحات  -

تاریخ انتشار 2009